Another region of the limbic system, the frontal cortex, is also impaired by drug use.
The frontal cortex is involved in logical thinking; making decisions about what stimuli requires attention; controlling impulsive behaviors, such as aggression; setting goals and ordering priorities (Fowler, J. S., et al. 2007).
Impairment of this region is believed to be responsible for addicts’ inability to forego the pleasure of drug use in favor of more responsible choices (Fowler, J. S., et al. 2007).
Smaller prefrontal lobes with diminished activity have been found in people who abuse alcohol, methamphetamine, cocaine and various other substances (Fowler, J. S., et al. 2007).